MicroRNA Sequencing

MicroRNA (miRNA) sequencing assesses small, noncoding RNA molecules to grant researchers insight into key biological functions for profiling and discovery applications. The Element AVITI™ System delivers consistent, accurate data at a price point that scales to serve a 2 x 75 read length and output of ~5–10 million reads per sample.

AVITI also offers the flexibility to explore both existing and novel miRNA:

  • High sequencing quality with high recovery
  • Consistent correlation and expression of miRNA
  • Ability to scale experiments for small inserts and lower output
  • Compatibility with third-party library preps via the Adept™ Workflow
Figure 1. Unique molecular identifier (UMI) reads prepared from Human Brain Reference Total (HBR) RNA and Human XpressRef Universal Total RNA (XR) and sequenced on AVITI average high quality scores (Q-scores) of 41–42. Element Biosciences (2023)
Figure 2. For each sample, miRBase annotated a high number of unique mRNA molecules. Each method of adapting libraries for sequencing on AVITI, Adept Rapid PCR-Free and Adept Rapid PCR-Plus, deliver similar results. Element Biosciences (2023)

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