Single-Cell RNA Sequencing
Single-cell sequencing is a powerful technique for revealing hidden complexity within cell populations. Element is a validated partner for 10X Genomics, BD Rhapsody, as well as emerging instrument-free cellular barcoding technologies. With an Element AVITI™ System, you can:
- Do more science for your budget with industry leading cost of $0.60 - $1 per million reads and guaranteed reagent costs for the life of your instrument.
- Maximize cost-efficiency with throughput that neatly matches the sample outputs from both leading and emerging single-cell technologies.
- Ensure sensitivity to low expressed genes and a high yield of genes per barcode with high quality data.
- Enable multiple run starts daily with two fully independent 1 billion-read flow cells, providing unrivaled sequencing access in multiuser environments.
- Use Cloudbreak Freestyle™ chemistry to load linear, third-party single-cell libraries directly on the AVITI System without manual circularization.
![](https://www.elementbiosciences.com/uploads/applications/_applicationsPhoto/single-cell-existing-image-redone-1.png)
Figure 1. AVITI performance on 10K and 1K human PBMC samples met or exceeded the quality metrics required by 10X genomics to be part of their Compatible Partner Program.
![](https://staging.elementbiosciences.com/uploads/applications/_applicationsPhoto/rna2.png)
Figure 2. AVITI performance using Cloudbreak and Cloudbreak Freestyle sequencing on a 40K cell sample comprised of human peripheral blood mononuclear cells (PBMC), human T cells, and baboon bone marrow cells (BBMC). The tSNE plot shows an overlap of Cloudbreak and Cloudbreak FS, indicating a strong overlap for PBMC cell samples. Cloudbreak FS or Adept library conversion combined with Cloudbreak both deliver similar results.
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