Poster: A novel integrated target capture and rapid sequencing workflow for myeloid malignancy mutation detection within 12 hours

Hybrid capture technology is a powerful and cost-effective tool to detect somatic mutations in n precision oncology research. While target capture is important for efficient mutation detection, obtaining rapid sequencing results is critical. Traditional hybrid capture workflows involve several time-consuming steps prior to sequencing which can delay results.

Here, we combine Trinity™ hybrid capture and a rapid AVITI™ sequencing protocol to deliver targeted sequencing results within 12 hours. We applied this specialized Trinity workflow with a custom myeloid panel based on a design used by Genomics Medicine Sweden to detect mutations in reference DNA and patient blood/bone marrow/fresh frozen tissue. This rapid, accurate, and robust solution for targeted sequencing, offers significant advancements in turnaround time for hematology malignancy research.

Download the poster

By submitting this form you agree to our Privacy Policy and Terms and Conditions.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.