Hybrid selection technologies allow highly efficient, accurate, and cost-effective sequencing of specific genomic regions. Trinity™ is our novel capture technology that revolutionizes traditional workflows by using a one-hour hybridization step followed by elimination of standard post-hybridization steps and integrates hybridization capture into the sequencing process. Download this poster to see how we extended this technology to validate panels ranging from 7,000 to >430,000 probes from major target capture panel vendors.
Highlights include:
- See how Trinity performs across hybrid selection panel sizes and vendors with high specificity, target coverage, and library diversity.
- Superior performance with exome and custom panels demonstrating higher on-target specificity, improved target coverage, and comparable variant calling recall and precision.
- Validation of Trinity for germline and somatic variant calling in clinical research applications using a custom panel for myeloid malignancy diagnostic research.