Applications

Designed to do more

From whole genomes to single-cell RNA, the AVITI™ System delivers unprecedented sequencing power in an affordable benchtop instrument. A range of applications enable you to do your experiments your way, on your timeline.

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DNA Sequencing

Scientists have a wide variety of methods they can use to access genomic information depending on the goals of their experiment. The Element AVITI System sequences DNA in a fundamentally new way, giving it unique strengths:

Negligible index hopping, preserving the integrity of multiplexed sample data
Low optical duplication rates, increasing the effective coverage of samples at a given sequencing depth
Unparalleled accuracy through homopolymer regions
Robust sequencing of low input samples, sharply reducing the required concentration of PhiX Control Library for methylation and amplicon sequencing
The ability to sequence inserts longer than 500 bp, improving genome assemblies and giving greater access to hard-to-sequence regions than other short read technologies

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Whole-Genome Sequencing

Get a comprehensive view of all the variants in human, plant, animal, or bacterial genomes with robust variant calling enabled by long library inserts and industry-leading accuracy.

Targeted Sequencing

Focus your sequencing on critical subsets of the genome or get in-depth coverage of informative genes or loci in complex populations with cost-effective sequencing and low batching requirements.

Low-Pass WGS

Sequence the entire genome at low or ultra-low coverage for genotyping or variant calling with imputation at a per-sample cost competitive with microarrays.

Methylation Sequencing

Get higher effective coverage of bisulfite-converted DNA samples with minimal PhiX Control Library spike-in requirements on the AVITI System.

16S Amplicon Sequencing

Uncover hidden complexity in cell populations with AVITI data that reveal more of the dynamic range of gene expression with improved detection of low-expressed genes.

RNA Sequencing

RNA sequencing is a powerful tool for understanding the biological state of a cell or population of cells. Gene expression data can help scientists elucidate the downstream consequences of genomic variants or understand the impact of changes to the cellular environment. The Element AVITI System lends unique strengths to RNA sequencing experiments:

Negligible index hopping, preserving the integrity of multiplexed sample data
Low optical duplication rates, increasing the effective coverage of samples at a given sequencing depth
Throughput conveniently matched to the sequencing requirements of typical single cell experimental designs
Isoform identification with LoopSeq technology

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Single-Cell RNA Sequencing

Uncover hidden complexity in cell populations with AVITI data that reveal more of the dynamic range of gene expression with improved detection of low-expressed genes.

MicroRNA Sequencing

Generate miRNA libraries from total RNA to explore existing miRNA and discover novel miRNA with high accuracy and high recovery enabled by industry-leading accuracy.