Webinar On-Demand: Optical Pooled CRISPR Screen Reveals Regulators of NF-κB Dynamics in Human Cells

In this webinar, Tilmann Buerckstuemmer, PhD, CSO of Myllia Biotechnology, presents an optical pooled CRISPR screen linking genetic perturbations to p65 subcellular localization and cell painting morphological features in a single automated workflow on the AVITI24™ platform. The multimodal readout recovered canonical pathway components and uncovered new regulatory roles for chromatin-modifying complexes.

Watch to learn:

• How to link CRISPR perturbations to protein localization and cell morphology at single-cell resolution
• Why multimodal readouts add interpretive confidence beyond transcriptomics
• How this approach supports mechanism-of-action studies and identification of both positive and negative regulators of signaling pathways