Elemental Re-thinking

Using a first-principles approach, Element Biosciences has invented new technical elements of a sequencing platform to offer the best combination of performance, cost, and flexibility on a benchtop system.

Visualization of Avidity Sequencingâ„¢ Chemistry by Element Biosciences as an Avidite Polymerase

Avidity Sequencingâ„¢ Chemistry

  • Delivers high data quality through enhanced contrast-to-noise ratio (CNR) and inherent error suppression mechanisms
  • Chemistry innovation significantly decreases costly reagent consumption
  • Produces scarless DNA products
  • Utilizes engineered, proprietary polymerases to reduce context errors
Visualization of Element Biosciences Surface Chemistry DNA Polony

Surface Chemistry

  • Ultra-low binding surfaces passivate the flow cell, creating negligible non-specific binding and increased CNR
  • Novel surface functionalization with sequence-specific oligos to ensure efficient library capture and utilization
  • Non-fouling surfaces are shipped and stored dry
  • Versatile surface production process enables seamless adoption of a breadth of surface assays and analyte types

Amplification

  • Surface amplification without polymerase error propagation and with a reduced bias for insert size and GC content
  • Eliminates amplification-induced library index swapping
  • Supports Element proprietary paired-end workflows and low sample input
  • Compatible with existing paired-end dual-indexed libraries

Onboard Analysis

  • Seamlessly extracts imaging data to base calls with quality scores in real-time
  • Sends data directly to your cloud without the need to wait for post-run analysis

Optical System

  • Offers unprecedented large field of view imaging with remarkable edge to edge quality
Technology

Learn More About Us

At Element Biosciences, we're constantly looking for new ways to improve our technology and our company. To find out more about our philosophy, values, and accomplishments, check out the links below.