Feasibility of a Complete PCR-free Whole Exome Sequencing Using a New Integrated Library Preparation and Sequencing Workflow

Whole exome sequencing (WES) is a robust and cost-effective approach for research detecting genetic variants across inherited diseases. WES workflows are complex, time-consuming, and can contribute to assay variability and limit sensitivity of the assay. In this poster, we present our new Trinity™ workflow that eliminates the need for PCR and integrates post-hybridization steps directly onto the AVITI™ sequencer.

Download the poster and learn how:

  • Trinity provides an improved PCR-free workflow for hybridization-based sequencing, including WES.
  • Significant performance improvements compared to traditional workflows, including more uniform coverage, lower duplication rates, and improved benchmarking.

Download the poster

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