Designed to do more
From whole genomes to single-cell RNA, the AVITI™ System delivers unprecedented sequencing power in an affordable benchtop instrument. A range of applications enable you to do your experiments your way, on your timeline.
DNA Sequencing
Scientists have a wide variety of methods they can use to access genomic information depending on the goals of their experiment. The Element AVITI System sequences DNA in a fundamentally new way, giving it unique strengths:
- Negligible index hopping, preserving the integrity of multiplexed sample data
- Low optical duplication rates, increasing the effective coverage of samples at a given sequencing depth
- Unparalleled accuracy through homopolymer regions
- Robust sequencing of low input samples, sharply reducing the required concentration of PhiX Control Library for methylation and amplicon sequencing
- The ability to sequence inserts longer than 500 bp, improving genome assemblies and giving greater access to hard-to-sequence regions than other short read technologies
RNA Sequencing
RNA sequencing is a powerful tool for understanding the biological state of a cell or population of cells. Gene expression data can help scientists elucidate the downstream consequences of genomic variants or understand the impact of changes to the cellular environment. The Element AVITI System lends unique strengths to RNA sequencing experiments:
- Negligible index hopping, preserving the integrity of multiplexed sample data
- Low optical duplication rates, increasing the effective coverage of samples at a given sequencing depth
- Throughput conveniently matched to the sequencing requirements of typical single cell experimental designs
- Isoform identification with LoopSeq technology
Long-Read Sequencing
Long-read sequencing provides the additional genomic context that is often needed to reveal the full complexity of biological systems. With LoopSeq, researchers can obtain highly accurate long-read information on a short-read platform without the need for a dedicated instrument.
LoopSeq provides access to:
- Isoform-resolved RNA sequencing data that can detect changes in gene expression that are invisible to short reads.
- Full-length 16S data needed to identify bacteria at the species or strain level.
- Immune repertoire data that reveal the full complexity of the immune response, including isotype or paired heavy and light chains.
- Long-read targeted sequencing data to detect gene fusions and fully phased mutations.