Element LoopSeq long-reads deliver highly accurate, unbiased, single molecule sequencing that can resolve and quantify subtly different clonotypes that other sequencing technologies miss.
Element LoopSeq Long-Reads Dramatically Change What You Can Learn about the Adaptive Immune System
- Understand the diversity of the immune cell repertoire with full-length, single molecule sequencing of B cell receptors, T cell receptors, immunoglobulins, and scFvs
- Sequence genomic DNA, mRNA, or both
- Quantify dynamic changes to immune cell populations with bias-free single molecule counting
- Characterize natural and synthetic immune repertoires easily and accurately
- Find and follow rare clonotypes
- Identify biomarker signatures
- Illumina short reads are far from long enough to completely sequence a full-length T cell receptor, immunoglobulin, or scFv.
- While long read platforms can provide the full-length sequence of a receptor's gene or transcript, they lack the accuracy needed for reliable, reproducible results.
- Fortunately, Loop Genomics's synthetic long read technology is ideally suited for studying the immune cell repertoire.
- Loop Long-reads deliver highly accurate, unbiased, single molecule sequencing that can resolve and quantify subtly different clonotypes that other sequencing technologies miss.
- You can gain insight into which variable and constant regions an individual clonotype or scFv contains as a result of our 99.9959% sequencing accuracy and read lengths of up to 6 kb with our LoopSeq technology