Element LoopSeq Long-Reads Dramatically Change What You Can Learn about the Adaptive Immune System
Understand the diversity of the immune cell repertoire with full-length, single molecule sequencing of B cell receptors, T cell receptors, immunoglobulins, and scFvs
Sequence genomic DNA, mRNA, or both
Quantify dynamic changes to immune cell populations with bias-free single molecule counting
Characterize natural and synthetic immune repertoires easily and accurately
Find and follow rare clonotypes
Identify biomarker signatures
Illumina short reads are far from long enough to completely sequence a full-length T cell receptor, immunoglobulin, or scFv.
While long read platforms can provide the full-length sequence of a receptor's gene or transcript, they lack the accuracy needed for reliable, reproducible results.
Fortunately, Loop Genomics's synthetic long read technology is ideally suited for studying the immune cell repertoire.
Loop Long-reads deliver highly accurate, unbiased, single molecule sequencing that can resolve and quantify subtly different clonotypes that other sequencing technologies miss.
You can gain insight into which variable and constant regions an individual clonotype or scFv contains as a result of our 99.9959% sequencing accuracy and read lengths of up to 6 kb with our LoopSeq technology