Staff / Senior Staff Scientist, Sequencing Biochemistry Reagent Development

San Diego, CA R&D - Reagent and Assay Development Full Time
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Element Biosciences is a multi-disciplinary startup focused on innovating genetic analysis tools for the research and clinical markets. The Company's technology will broaden the end user experience through improved data quality and simplified workflows to benefit discoveries and diagnosis in healthcare. We are seeking a high-level technical lead Staff Scientist for biochemistry development of enzymatic reagents for our NGS platform.  You will plan, create framework, chart timelines, budget capital equipment purchases, build a team to execute development projects around characterization, optimization through DOE/scientific acumen, and delivery of robust reagents to Ops & Mfg. You will design assays and strategies to improve performance, troubleshoot problems, discover novel solutions, support /invent QC framework for Ops&Mfg.  Success in this position requires communicating across all levels in the organization and requires strong relationships that are built on a foundation of respect, integrity, cooperation, teamwork, and professionalism.  

Responsibilities

  • Build a team to execute development projects around characterization, optimization through DOE/scientific acumen, and delivery of robust reagents to Operations and Manufacturing
  • Support and invent QC framework for Operations and Manufacturing
  • Design assays and strategies to improve performance
  • Plan, create framework, and chart timelines for projects
  • Budget capital equipment purchases
  • Troubleshoot problems and discover novel solutions

Requirements

  • Doctor of Philosophy (Ph.D.) in chemistry, biochemistry, molecular biology, bioengineering or a related discipline
  • Minimum of 7 years industry-related experience
  • Strong scientific background in biochemistry of DNA/RNA processing enzymes (polymerases a must, others a plus) and nucleic acids
  • Strong experience with analytical, biophysical, and biochemical tools and assays
  • Proven track record of in both early and late stages development in commercialization of enzymatic biochemistry reagents and in building teams

Other Knowledge & Skills

  • Strong knowledge in protein stability   
  • Ability to develop surrogate assays predictive of sequencing reagent performance
  • Ability to deliver required reagent performance and stability through understanding of biochemical and biophysical principals/fundamentals
  • Demonstrated complex problem-solving on complex systems
  • Proven ability to anticipate, plan, predict and prepare for issues
  • Proven ability to make high risk decisions with limited data
  • Highly detail oriented and able to adapt quickly
  • Able to seek collaboration, know how to combine and synthesize information for a new purpose
  • Advanced project management skills
  • Excellent management and interpersonal skills
  • Have a growth mindset
  • Curious by nature, have fundamental drive to learn, and strong knowledge of scientific literature
We are passionate about our mission to develop high performing products to study genomics in an unprecedented flexibility and to understand biology for the improvement of healthcare. We have built a highly efficient product-driven organization where employees can learn, grow and thrive in a challenging but encouraging environment.  We are committed to scientific integrity, collegiality, honesty, objectivity, and openness.   We offer excellent benefits, which include a 401K plan, competitive health benefits, flexible vacation, and equity incentives.  We foster an environment such that all people are afforded the freedom to pursue their passions without regard to race, color, religion, national or ethnic origin, gender (including pregnancy), sexual orientation, gender identity or expression, age, disability, veteran status or any other characteristics protected by law.